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Clone competition as a mechanism to reduce tumor formation

Amelia Acha-Sagredo1, Ilaria Malanchi2, Francesca D Ciccarelli1

  • 1Cancer Systems Biology Laboratory, The Francis Crick Institute, London NW1 1AT, UK; School of Cancer and Pharmaceutical Sciences, King's College London, London SE1 1UL, UK.

Developmental Cell
|December 21, 2021
PubMed
Summary

As we age, mutated clones in tissues are common but rarely cause cancer. A study in Nature reveals that competition among these clones can surprisingly protect against tumor development.

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