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Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
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Management of Stage III Non-Small-Cell Lung Cancer: ASCO Guideline
Megan E Daly1, Navneet Singh2, Nofisat Ismaila3
1University of California, Davis, CA.
Summary
This guideline offers evidence-based recommendations for managing stage III non-small-cell lung cancer (NSCLC). It covers evaluation, surgical options, and treatment for unresectable cases, aiding clinicians in patient care.
Area of Science:
- Oncology
- Thoracic Surgery
- Radiation Oncology
Background:
- Stage III non-small-cell lung cancer (NSCLC) presents complex management challenges.
- Optimal treatment strategies require up-to-date, evidence-based guidance for clinicians.
Purpose of the Study:
- To develop evidence-based recommendations for the clinical management of stage III NSCLC.
- To provide guidance on evaluation, staging, and treatment modalities for NSCLC.
Main Methods:
- A multidisciplinary Expert Panel conducted a systematic literature search (1990-2021).
- Included systematic reviews, meta-analyses, and randomized controlled trials.
- Recommendations were formulated using available evidence and expert consensus.
Main Results:
- 127 relevant studies were identified to form the evidence base.
- Recommendations address diagnostic workup, surgical interventions, and neoadjuvant/adjuvant therapies.
- Guidance is provided for both resectable and unresectable stage III NSCLC.
Conclusions:
- Comprehensive recommendations are established for stage III NSCLC management.
- The guideline supports informed clinical decision-making for practicing physicians.
- Further information is available at www.asco.org/thoracic-cancer-guidelines.
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