Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

DOACs vs Warfarin for Post-myocardial Infarction Left Ventricular Thrombus: A GRADE-assessed Meta-Analysis With Trial Sequential Analysis of Randomized Trials.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·2026

Same author

SpatioTemporal Omics Consortium: a global effort for biological discovery across species, space and time.

Nature methods·2026

Same author

ExPO: an exposure-conditioned neural operator for L1000 signature prediction.

Journal of cheminformatics·2026

Same author

Comparison of Analgesic Efficacy of Intrathecal Morphine and Ultrasound-Guided Bilateral Erector Spinae Plane Block in Patients Undergoing Open Heart Surgery with Midline Sternotomy: An Open Label Randomized Control Trial.

Annals of cardiac anaesthesia·2026

Same author

Expert Consensus Framework for Standardizing Lung Ultrasound Training for Neonatologists Issued by ESPNIC Neonatal Critical Care Section and Point-of-Care Ultrasound Working Group.

Chest·2026

Same author

The Inheritance Puzzle: A Case of Dual Genetic Kidney Disease.

Nephrology (Carlton, Vic.)·2026

Search research articles

Related Experiment Video

Updated: Oct 9, 2025

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

Meta-Analysis Comparing Outcomes With Bifurcation Percutaneous Coronary Intervention Techniques.

Ayman Elbadawi¹, Mina Shnoda², Alexander Dang³

¹Department of Cardiovascular Medicine and; Division of Cardiology, Baylor College of Medicine, Houston, Texas.

The American Journal of Cardiology

|December 23, 2021

Summary

This meta-analysis found no significant difference in major adverse cardiac events (MACE) between one-stent and two-stent approaches for percutaneous coronary intervention (PCI) bifurcation lesions. However, the double kissing crush technique showed promising results for reducing MACE and other adverse events.

More Related Videos

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model

Published on: November 24, 2014

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

Related Experiment Videos

Last Updated: Oct 9, 2025

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model

Published on: November 24, 2014

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

Area of Science:

Cardiology
Interventional Cardiology
Medical Devices

Background:

Percutaneous coronary intervention (PCI) bifurcation techniques have shown varied efficacy and safety outcomes.
Optimizing PCI for bifurcation lesions remains a challenge in interventional cardiology.

Purpose of the Study:

To compare the efficacy and safety of one-stent versus two-stent PCI bifurcation approaches.
To evaluate different bifurcation techniques using network meta-analysis.

Main Methods:

Systematic electronic search of Medline, Scopus, and Cochrane databases for randomized controlled trials.
Pairwise meta-analysis comparing one-stent vs. two-stent approaches.
Network meta-analysis comparing various bifurcation techniques.
Primary outcome: Major Adverse Cardiac Events (MACE).

Main Results:

No significant difference in MACE between one-stent and two-stent approaches (RR 1.20, 95% CI 0.92-1.56) over a weighted follow-up of 25.9 months.
Exploratory analysis suggested increased MACE with one-stent approach in specific scenarios (second-generation DES, long side branch, final kissing balloon).
Network meta-analysis indicated double kissing crush technique associated with lower MACE, MI, TVR, and target lesion revascularization; culotte technique linked to higher stent thrombosis.

Conclusions:

One-stent and two-stent PCI bifurcation strategies show comparable long-term MACE risk.
The double kissing crush technique appears superior among evaluated bifurcation techniques, associated with reduced MACE and target lesion revascularization.