Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Investigation of Annealing Temperature Effect of Tin Oxide on the Efficiency of Planar Structure Perovskite Solar Cells.

Nanomaterials (Basel, Switzerland)·2025
Same author

On-chip non-contact mechanical cell stimulation - quantification of SKOV-3 alignment to suspended microstructures.

Heliyon·2025
Same author

The reversible capillary field effect transistor: a capillaric element for autonomous flow switching.

Lab on a chip·2025
Same author

Laminar flow-based microfluidic systems for molecular interaction analysis-Part 2: Data extraction, processing and analysis.

Methods in enzymology·2023
Same author

Laminar flow-based microfluidic systems for molecular interaction analysis-Part 1: Chip development, system operation and measurement setup.

Methods in enzymology·2023
Same author

A pilot study using unique targeted testing of the urogenital microbiome has potential as a predictive test during IVF for implantation outcome.

Archives of gynecology and obstetrics·2023

Related Experiment Video

Updated: Oct 9, 2025

Conformable Wearable Electrodes: From Fabrication to Electrophysiological Assessment
10:03

Conformable Wearable Electrodes: From Fabrication to Electrophysiological Assessment

Published on: July 22, 2022

4.6K

Conductive Bioimprint Using Soft Lithography Technique Based on PEDOT:PSS for Biosensing.

Nor Azila Abd Wahid1, Azadeh Hashemi1, John J Evans2

  • 1Department of Electrical and Computer Engineering, The MacDiarmid Institute for Advanced Materials and Nanotechnology, University of Canterbury, Christchurch 8140, New Zealand.

Bioengineering (Basel, Switzerland)
|December 23, 2021
PubMed
Summary

Researchers developed a novel conductive hydrogel (CH) with bioimprinted surface features. This biocompatible material accurately replicates cell morphology, enhancing cell monitoring and biosensing applications.

Keywords:
PEDOT:PSSconductive bioimprintconductive hydrogelelectrical conductivitysoft lithography

More Related Videos

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor
11:17

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor

Published on: February 10, 2014

11.9K
Bioinspired Soft Robot with Incorporated Microelectrodes
08:24

Bioinspired Soft Robot with Incorporated Microelectrodes

Published on: February 28, 2020

9.0K

Related Experiment Videos

Last Updated: Oct 9, 2025

Conformable Wearable Electrodes: From Fabrication to Electrophysiological Assessment
10:03

Conformable Wearable Electrodes: From Fabrication to Electrophysiological Assessment

Published on: July 22, 2022

4.6K
Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor
11:17

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor

Published on: February 10, 2014

11.9K
Bioinspired Soft Robot with Incorporated Microelectrodes
08:24

Bioinspired Soft Robot with Incorporated Microelectrodes

Published on: February 28, 2020

9.0K

Area of Science:

  • Biomaterials Science
  • Cell Biology
  • Surface Engineering

Background:

  • Surface topography significantly influences cell behavior, crucial for lab-on-a-chip devices, medical implants, and biosensors.
  • Understanding cell responses to topographical cues is vital for advancing tissue engineering and regenerative medicine.

Purpose of the Study:

  • To develop a novel biocompatible conductive hydrogel (CH) with bioimprinted surface features for cell culture.
  • To investigate cellular responses, including growth, adhesion, and proliferation, to conductivity and topographical cues.
  • To create a platform for improved cell monitoring and biosensing applications.

Main Methods:

  • Fabrication of a conductive hydrogel (CH) using poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) and gelatin.
  • Bioimprinting of surface features onto the CH to replicate cellular morphology.
  • Characterization of replication fidelity using Atomic Force Microscopy (AFM).
  • Measurement of electrical conductivity before and after crosslinking.

Main Results:

  • The bioimprinted CH demonstrated high replication fidelity (>90%) of cellular features.
  • Crosslinking significantly increased the electrical conductivity of the CH from 10^-6 S/cm to 1 S/cm.
  • The material exhibited high conductivity, biocompatibility, and suitability for cell culture.

Conclusions:

  • The developed conductive bioimprinted hydrogel offers a promising platform for advanced cell culture and monitoring.
  • This technology has potential applications in biosensing and monitoring implant-tissue interactions.
  • The high replication fidelity and tunable conductivity pave the way for mimicking the cellular microenvironment.