The human bladder carcinoma line T-24 secretes a human B-cell differentiation factor
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Updated: Oct 23, 2026

Mouse Bladder Wall Injection
Published on: July 12, 2011
Abstract:
The effect of a B-cell differentiation factor (BCDF) found in the supernatant of the human bladder carcinoma cell line T-24 (T-24.BCDF) was assessed using the human lymphoblastoid line CESS (Muraguchi et al., 1981) and TPA-stimulated human B-CLL B cells. This T-24.BCDF was shown to cause both these cell types to secrete immunoglobulin, and therefore indicates that culture supernatants from this bladder carcinoma line contain a potent differentiation factor for human B cells.
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