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Sex-Specific Differences in Outcomes Following Thyroidectomy: A Population-Based Cohort Study.
Lara Gut1, Selina Bernet1, Monika Huembelin1
1Division of Endocrinology, Diabetes, and Metabolism, University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland.
European Thyroid Journal
|December 24, 2021
Summary
Male thyroidectomy patients face higher readmission and ICU admission rates. They also have increased risks of hematoma, while females experience more hypocalcemia post-surgery.
Area of Science:
- Endocrinology
- Surgical Outcomes
- Health Services Research
Background:
- Thyroidectomy rates and quality measure awareness are increasing.
- Sex-specific variations in thyroidectomy outcomes require further investigation.
Purpose of the Study:
- To investigate sex-specific differences in patient outcomes following thyroidectomy.
Main Methods:
- Population-based cohort study in Switzerland (2011-2015).
- Included adult patients undergoing hemi- or total thyroidectomy.
- Primary outcome: 30-day all-cause readmission; Secondary outcomes: ICU admission, re-intervention, mortality, length of stay, calcium disorder, vocal cord paresis, hematoma.
Main Results:
- Male patients had significantly higher 30-day hospital readmission (RR 1.38) and ICU admission (RR 1.25) rates.
- Males showed increased risk of postoperative hematoma (RR 1.93), while females had higher rates of hypocalcemia.
- No significant sex differences in length of stay, re-intervention, or in-hospital mortality.
Conclusions:
- Male patients undergoing thyroidectomy experience higher 30-day hospital readmission and ICU admission rates.
- Post-thyroidectomy, males have a greater risk of neck hematoma, whereas females are more prone to hypocalcemia.
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