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Pancreatic imaging using diffusivity mapping - Influence of sequence technique on qualitative and quantitative

Anoshirwan Andrej Tavakoli1, Constantin Dreher2, Anna Mlynarska1

  • 1German Cancer Research Center (DKFZ), Department of Radiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

Clinical Imaging
|December 25, 2021
PubMed
Summary

An advanced diffusion weighted imaging (DWI) sequence significantly improved pancreatic imaging quality, detail, and boundary definition compared to standard DWI. This optimized sequence offers superior visualization for pancreatic assessment.

Keywords:
ArtifactsDiffusion magnetic resonance imagingEcho-planar imagingMagnetic resonance imagingPancreas

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Area of Science:

  • Radiology
  • Medical Imaging
  • Diffusion Weighted Imaging

Background:

  • Standard diffusion-weighted imaging (DWI) protocols can be limited in pancreatic imaging.
  • Optimized DWI sequences with advanced post-processing and motion correction aim to enhance image quality.

Purpose of the Study:

  • To compare the image quality of an advanced DWI sequence (advanced-EPI) with a standard DWI protocol (standard-EPI) in pancreatic imaging.
  • To evaluate parameters such as image quality, parenchymal detail, boundary sharpness, and discernibility from adjacent structures.

Main Methods:

  • Retrospective analysis of 62 patients undergoing abdominal MRI at 1.5 T.
  • Comparison of standard-EPI and advanced-EPI DWI sequences.
  • Radiologist evaluation of image quality using a Likert-like scale.
  • Calculation of apparent diffusion coefficient (ADC) and tissue-to-background ratio (TBR).

Main Results:

  • Advanced-EPI demonstrated significantly higher scores for image quality, parenchymal detail, boundary sharpness, and discernibility (p < 0.001).
  • Radiologists preferred advanced-EPI in 96% of cases.
  • Advanced-EPI showed a 7% lower pancreatic ADC (p < 0.001) and a 51% higher TBR at b=900 s/mm² (p < 0.001).

Conclusions:

  • An advanced DWI sequence significantly enhances image quality in pancreatic imaging.
  • Improved parenchymal detail and visualization are achieved with the advanced sequence.
  • Advanced DWI protocols may offer superior diagnostic performance for pancreatic assessment.