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Absence of clinical benefit of FDG PET-CT in staging T1 part-solid lung adenocarcinoma
D Pencharz1, S Modi1, S Bandyopadhyay2
1Department of Nuclear Medicine, The Royal Free Hospital, Royal Free London NHS Foundation Trust, Pond Street, London, NW3 2QG, UK.
Aim:
To assess the rates of nodal and metastatic disease and change in management when staging part-solid T1 lung adenocarcinomas using integrated 2-[18F]-fluoro-2-deoxy-d-glucose (FDG) positron-emission tomography (PET)-computed tomography (CT) in a UK population.
Materials And Methods:
This was a retrospective review of PET-CT examinations performed to stage radiologically suspected T1 part-solid lung adenocarcinoma (n=58) from two different centres. Rates of detection of nodal and metastatic disease, change in management, and final patient outcome were recorded.
Results:
PET-CT changed the stage in one patient from N0 to N1. It did not change final management in any patient.
Conclusions:
In this UK population, PET-CT had minimal additional diagnostic benefit in staging patients with T1 part-solid lung adenocarcinoma. Especially given its cost, the inclusion of PET-CT for this indication in guidelines should be reviewed.
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