Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An Emergence Framework of Carcinogenesis.

Frontiers in oncology·2017
Same author

Surgical margins in head and neck squamous cell carcinoma: Effect of heat artifact on immunohistochemistry as a future tool for assessment.

Head & neck·2016
Same author

Concha bullosa: reducing middle meatal adhesions by preserving the lateral mucosa as a posterior pedicle flap.

The Journal of laryngology and otology·2004
See all related articles

Related Experiment Video

Updated: Oct 8, 2025

3D Printing of Preclinical X-ray Computed Tomographic Data Sets
11:06

3D Printing of Preclinical X-ray Computed Tomographic Data Sets

Published on: March 22, 2013

40.7K

How 3D Printing Is Reshaping Translational Research.

Elizabeth A W Sigston1,2,3

  • 1Monash Institute of Medical Engineering, Monash University, Melbourne, VIC, Australia.

Frontiers in Bioengineering and Biotechnology
|December 27, 2021
PubMed
Summary

Additive manufacturing, or 3D printing, is revolutionizing translational research by enabling faster innovation and bidirectional collaboration. While offering immense benefits, careful management of ethical and regulatory challenges is crucial for its successful implementation.

Keywords:
3D printingadditive manufacturingbioengineeringbiomedicaldesign methodologyentrepreneurshipsystems biologytranslational research

More Related Videos

3D Printing of Biomolecular Models for Research and Pedagogy
09:17

3D Printing of Biomolecular Models for Research and Pedagogy

Published on: March 13, 2017

24.3K
Voxel Printing Anatomy: Design and Fabrication of Realistic, Presurgical Planning Models through Bitmap Printing
11:36

Voxel Printing Anatomy: Design and Fabrication of Realistic, Presurgical Planning Models through Bitmap Printing

Published on: February 9, 2022

2.9K

Related Experiment Videos

Last Updated: Oct 8, 2025

3D Printing of Preclinical X-ray Computed Tomographic Data Sets
11:06

3D Printing of Preclinical X-ray Computed Tomographic Data Sets

Published on: March 22, 2013

40.7K
3D Printing of Biomolecular Models for Research and Pedagogy
09:17

3D Printing of Biomolecular Models for Research and Pedagogy

Published on: March 13, 2017

24.3K
Voxel Printing Anatomy: Design and Fabrication of Realistic, Presurgical Planning Models through Bitmap Printing
11:36

Voxel Printing Anatomy: Design and Fabrication of Realistic, Presurgical Planning Models through Bitmap Printing

Published on: February 9, 2022

2.9K

Area of Science:

  • Biomedical Engineering
  • Translational Medicine
  • Medical Device Development

Background:

  • Traditional translational research follows a unidirectional "bench to bedside" model.
  • Additive manufacturing (3D printing) is introducing new paradigms in medical innovation.
  • The rise of systems biology complements rapid advancements in translational research.

Purpose of the Study:

  • To explore the impact of 3D printing on translational medical research.
  • To discuss the shift towards bidirectional and collaborative research models.
  • To identify potential challenges and ethical considerations associated with 3D printing in medicine.

Main Methods:

  • Literature review and conceptual analysis of additive manufacturing in translational research.
  • Examination of the interplay between 3D printing, systems biology, and collaborative research.
  • Analysis of regulatory, ethical, and clinical outcome assessment challenges.

Main Results:

  • 3D printing facilitates personalized medicine and accelerates the translation of basic science to clinical practice.
  • It fosters bidirectional translation, early interdisciplinary collaboration, and an entrepreneurial approach.
  • Potential pitfalls include regulatory lags, challenges in outcome assessment, and conflicts of interest.

Conclusions:

  • 3D printing is fundamentally reshaping translational research, enabling faster and more personalized medical solutions.
  • Proactive management of ethical and regulatory issues is essential to harness the full potential of this technology.
  • The impact of 3D printing extends beyond device development, influencing the broader landscape of biomedical research and scientific thinking.