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Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
Published on: February 29, 2020
Chyle leak occurring after vagal nerve stimulator implantation in a child
Nolan Winslow1, Sonia Pulido2, Jonathan Garst3
1Department of Neurosurgery, OSF Saint Francis Medical Center, Peoria IL, 61637, USA; University of Illinois College of Medicine, 1 Illini Drive, Peoria, IL 61605, USA.
Insights
Vagus nerve stimulation for epilepsy carries risks, including rare but serious chyle leaks from thoracic duct injury. Management involves dietary changes, medication, or surgery for persistent cases.
Area of Science:
- Neurosurgery
- Thoracic Surgery
- Gastroenterology
Background:
- Vagus nerve stimulation (VNS) is an established therapy for medically-refractory epilepsy.
- Standard VNS risks include infection, hoarseness, and hardware issues.
- Chyle leak, a complication of thoracic and head/neck surgeries, is infrequently reported in neurosurgery.
Purpose of the Study:
- To highlight chyle leak as a potential complication of vagus nerve stimulation surgery.
- To discuss the clinical presentation and management strategies for chyle leak in this context.
Main Methods:
- Literature review of chyle leak complications in thoracic and head/neck surgeries.
- Analysis of reported cases and management protocols for chyle leak.
- Discussion of neurosurgical implications and treatment options.
Main Results:
- Chyle leak, though rare, can occur secondary to vagus nerve stimulation procedures.
- Severe chyle leaks can lead to significant nutritional deficiencies and immunosuppression.
- Management options range from conservative (diet, octreotide) to surgical ligation.
Conclusions:
- Chyle leak is an under-recognized complication of vagus nerve stimulation.
- Early recognition and appropriate management are crucial for patient outcomes.
- Further research may elucidate the precise incidence and optimal treatment strategies.
Abstract:
Vagus nerve stimulation is a therapy indicated for some patients with medically-refractory epilepsy. Typical risks of this procedure include infection, hoarseness, vocal cord dysfunction, and hardware malfunction. Chyle leak via injury to the thoracic duct is a known complication of thoracic and head and neck surgeries-though less so in the neurosurgical literature. In severe cases, chyle leak can lead to nutritional deficiencies and immunosuppression. Management of chyle leak includes low-fat diet and pharmacological suppression of chyle production with medications such as octreotide. If leak is persistent, surgical exploration with attempted ligation of lymphatic structures is performed.
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