Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nucleic Acid Structure01:25

Nucleic Acid Structure

7.5K
The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
DNA Structure
DNA...
7.5K
Homologous Recombination02:31

Homologous Recombination

5.1K
5.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A multiple-encrypted DNA device for secure communication.

Science advances·2026
Same author

Sprayable lipid-based lubricated hydrogel coating for alleviating catheter-related mucosal damage and pain.

Bioactive materials·2026
Same author

Material-Encoded Synchronization of Immunogenic Cell Death With Adenosine A2A Receptor Blockade Reprograms the Tumor Microenvironment.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Programming Dimensional Transitions in DNA Brick Crystals via Interfacial Connectivity.

Angewandte Chemie (International ed. in English)·2026
Same author

Structure-Controlled Molecular Recognition and Charge Transport in Metallized DNA Nanosheets.

Journal of the American Chemical Society·2026
Same author

Fusogenic Polymer-Liposome-Hybrid Nanoparticle: A Versatile Platform for Synchronized Drug Delivery to the Cytoplasm and Cell Membrane.

Polymer science & technology (Washington, D.C.)·2026
Same journal

A Domino-Synthesized Dicoordinate Copper(I) Bis-imidazopyridine Complex Triggering Cuproptosis/Ferroptosis for Enhanced Cancer Immunotherapy.

Angewandte Chemie (International ed. in English)·2026
Same journal

Mirror-Symmetric Organic Two-Dimensional Crystals for Alternative Photon Transport Pathways.

Angewandte Chemie (International ed. in English)·2026
Same journal

Cobalt-Catalyzed Migratory E-Selective Asymmetric Aza-Nozaki-Hiyama-Kishi Coupling.

Angewandte Chemie (International ed. in English)·2026
Same journal

Facile Synthesis of α,ω-Dihydroxy Telechelic Macromonomers From Ethylene and α-Olefins for Recyclable Alternating Block Copolymers.

Angewandte Chemie (International ed. in English)·2026
Same journal

Multi-Atom Sub-Nanometer Assemblies on Interpenetrating Multi-Chambered N/C Nanospheres.

Angewandte Chemie (International ed. in English)·2026
Same journal

A Synergistic C<sub>2+</sub> Alcohols/Olefins-Intermediated Pathway Boosts CO<sub>2</sub> Hydrogenation to Aromatics.

Angewandte Chemie (International ed. in English)·2026
See all related articles

Related Experiment Video

Updated: Oct 8, 2025

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
08:59

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

Published on: September 27, 2019

11.7K

DNA Origami-Encoded Integration of Heterostructures.

Xinpei Dai1,2,3, Xiaoliang Chen4, Xinxin Jing4,5

  • 1Division of Physical Biology, CAS Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China.

Angewandte Chemie (International Ed. in English)
|December 28, 2021
PubMed
Summary
This summary is machine-generated.

This study introduces a DNA origami method for precisely integrating silica and metal nanoparticles. This nanotechnology enables bottom-up fabrication of novel electronic and optoelectronic devices.

Keywords:
DNA metallizationDNA nanotechnologyDNA origamiDNA silicification

More Related Videos

Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

14.7K
Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates
09:17

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates

Published on: March 5, 2019

8.8K

Related Experiment Videos

Last Updated: Oct 8, 2025

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
08:59

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

Published on: September 27, 2019

11.7K
Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

14.7K
Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates
09:17

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates

Published on: March 5, 2019

8.8K

Area of Science:

  • Nanotechnology
  • Materials Science
  • Electronics

Background:

  • Integrating diverse materials at the nanoscale is essential for advanced electronics.
  • DNA nanotechnology offers precise material assembly but has not been used for heterogeneous integration.
  • Previous methods lacked precise control over dissimilar material placement on nanostructures.

Purpose of the Study:

  • To develop and demonstrate a DNA origami-encoded strategy for the heterogeneous integration of silica-metal heterostructures.
  • To investigate the mechanisms governing the deposition of silica and metal clusters on DNA nanostructures.
  • To achieve high-precision, site-specific assembly of dissimilar nanomaterials.

Main Methods:

  • Utilized DNA origami as a scaffold for programmed material deposition.
  • Employed theoretical and experimental studies to understand silica/metal cluster binding to DNA.
  • Manipulated DNA origami design (dsDNA strand density and length) to control material placement.
  • Demonstrated deposition with 2 nm vertical precision.

Main Results:

  • Identified distinct binding and aggregation mechanisms for silica and metal clusters on DNA.
  • Showcased independent deposition of silica and metal materials at predefined locations.
  • Achieved high site addressability in the integration of silica-gold and silica-silver heterostructures.
  • Verified the critical role of binding energy differences in material accessibility.

Conclusions:

  • The developed DNA nanotechnology strategy enables precise, bottom-up integration of dissimilar materials.
  • This approach is versatile and applicable to a wide range of material combinations.
  • Opens new possibilities for fabricating complex nanodevices for electronics and optoelectronics.