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Related Experiment Video

Updated: Oct 8, 2025

Author Spotlight: Developing a Disposable Dosator for Preclinical Testing of Dry Powder Inhalers in Small Animal Models
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Investigating the Accuracy of the Digihaler, a New Electronic Multidose Dry-Powder Inhaler, in Measuring Inhalation

Henry Chrystyn1, Dinesh Saralaya2, Anil Shenoy2

  • 1Inhalation Consultancy Ltd., Leeds, United Kingdom.

Journal of Aerosol Medicine and Pulmonary Drug Delivery
|December 29, 2021
PubMed
Summary

The Digihaler accurately measures inhalation parameters like peak inspiratory flow and inhaled volume in asthma and COPD patients. This digital inhaler provides reliable data for both patients and healthcare professionals.

Keywords:
digital technologydry powder inhalersinhalation deviceslung diseases

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Area of Science:

  • Respiratory Medicine
  • Medical Device Technology

Background:

  • The Digihaler is an FDA-approved digital inhaler providing feedback on inhalation technique and adherence.
  • Accurate measurement of inhalation parameters is crucial for effective respiratory disease management.

Purpose of the Study:

  • To compare inhalation parameters measured by the Digihaler against a simultaneous measurement from an inhalation profile recorder (IPR).
  • To validate the accuracy of the Digihaler's electronic module in capturing key inhalation metrics.

Main Methods:

  • An open-label, single-visit study enrolled pediatric and adult patients with asthma and adult patients with COPD.
  • Participants performed three inhalations with the Digihaler, simultaneously recorded by an IPR.
  • Peak inspiratory flow (PIF) and inhaled volume (inhV) were analyzed from both devices.

Main Results:

  • 148 participants provided usable inhalation data.
  • Mean PIF difference between Digihaler and IPR was -1.75% (strong correlation, r=0.96).
  • Mean inhV difference was -6.11%, with strong correlation between devices.

Conclusions:

  • The Digihaler demonstrates accurate measurement capabilities for critical inhalation parameters.
  • Findings support the Digihaler's utility in providing reliable data for patient and clinician use.
  • The device can effectively monitor inhalation technique and adherence in respiratory patients.