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An unusual case of a gallbladder polyp
T Lamiroy1, D Vogelaers2, P J Poortmans3
1Department of Gastroenterology, University hospital Ghent, Belgium.
Acta Gastro-Enterologica Belgica
|December 29, 2021
Summary
Hypereosinophilic syndrome can affect the gallbladder, mimicking cancer. Early diagnosis and corticosteroid treatment led to complete recovery in a patient with gallbladder eosinophilic infiltration.
Area of Science:
- Gastroenterology
- Hematology
- Oncology
Background:
- Hypereosinophilic syndrome (HES) is a rare disorder characterized by persistent eosinophilia.
- HES can involve multiple organ systems, including the nervous system and lungs.
- Gallbladder involvement in HES is uncommon but can present as a mass mimicking malignancy.
Observation:
- A 63-year-old female with a history of HES presented with an incidentally discovered gallbladder polyp.
- The polyp rapidly increased in size from 19mm to 36mm within one month.
- Imaging suggested gallbladder cancer, prompting surgical intervention.
Findings:
- Pathological examination revealed eosinophilic infiltration of the gallbladder, not malignancy.
- Elevated serum eosinophil counts confirmed active HES.
- The patient was diagnosed with HES involving the gallbladder.
Implications:
- This case highlights the importance of considering HES in the differential diagnosis of gallbladder masses, especially in patients with a history of the syndrome.
- Prompt diagnosis and appropriate management, including corticosteroid augmentation, are crucial for favorable outcomes.
- Successful treatment prevented further organ damage and led to complete patient recovery.
Keywords:
eosinophiliaeosinophilic cholangiopathyeosinophilic cholecystitisgallbladder cancergallbladder polyphypereosinophilic syndromeMore Related Videos
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