Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

2.0K
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
2.0K
Flail Chest-II01:26

Flail Chest-II

278
Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
278
Endoscopic Studies II: Thoracocentesis01:26

Endoscopic Studies II: Thoracocentesis

610
Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
610
Pneumothorax-II01:27

Pneumothorax-II

441
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
441
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

377
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
377
Flail Chest-I01:24

Flail Chest-I

327
Overview of Flail Chest
Flail chest is a severe and potentially life-threatening condition characterized by the fracture of three or more adjacent ribs in multiple places. It is most commonly caused by direct impacts and trauma, such as motor vehicle accidents or injuries from a steering wheel impact. It can also occur due to falls in elderly individuals with osteoporosis, or assaults involving sharp objects.
Pathophysiology
The pathophysiology of flail chest is complex, involving fractures of...
327

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Altered bone structure in Niemann-Pick Type C1 mice, especially in females.

Bone·2026
Same author

Clinical practice and implications of biomarker testing in biliary tract cancer: An observational study.

JHEP reports : innovation in hepatology·2026
Same author

Stratifying high-risk prediabetes clusters using blood-based epigenetic markers.

Biomarker research·2026
Same author

Risk Factors for Premature Exchange of Percutaneous Biliary Drainage in Benign and Malignant Biliary Strictures: A Retrospective Single-Center Study.

Visceral medicine·2025
Same author

Overexpression of KMT9α is associated with poor outcome in cholangiocarcinoma patients.

Journal of cancer research and clinical oncology·2025
Same author

Evaluation of an <i>IDH1/2</i> Mutation FastTrack Assay for Patients with Cholangiocarcinoma.

Cancers·2025

Related Experiment Video

Updated: Oct 8, 2025

Refined Murine Model of Idiopathic Pulmonary Fibrosis
07:51

Refined Murine Model of Idiopathic Pulmonary Fibrosis

Published on: June 17, 2025

387

Rounded atelectasis after exposure to refractory ceramic fibres (RCF).

Ulrike Brueckner1, Anne S Schulze2, Dirk Walter2,3

  • 1Institute and Outpatient Clinic for Occupational and Social Medicine, Justus-Liebig-University, Aulweg 129, 35392, Giessen, Germany. ulrike.brueckner@arbmed.med.uni-giessen.de.

Particle and Fibre Toxicology
|December 30, 2021
PubMed
Summary

Refractory ceramic fibres (RCF) exposure can cause lung issues similar to asbestos. Regular lung function tests and CT scans are crucial for early diagnosis in RCF-exposed workers.

Keywords:
Aluminium silicate fibresOccupational diseasesRCFRestrictive lung function patternRounded atelectasisThermal insulation

More Related Videos

An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing
09:29

An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing

Published on: May 13, 2020

11.8K
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.0K

Related Experiment Videos

Last Updated: Oct 8, 2025

Refined Murine Model of Idiopathic Pulmonary Fibrosis
07:51

Refined Murine Model of Idiopathic Pulmonary Fibrosis

Published on: June 17, 2025

387
An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing
09:29

An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing

Published on: May 13, 2020

11.8K
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.0K

Area of Science:

  • Occupational Medicine
  • Pulmonology
  • Materials Science

Background:

  • Refractory Ceramic Fibres (RCF) are man-made mineral fibres used in high-performance thermal insulation.
  • RCF share similarities with asbestos, being respirable, persisting in lungs for over 20 years, and potentially causing pleural changes.
  • Reported pleural changes include thickening and calcification.

Purpose of the Study:

  • To investigate the occupational health effects of Refractory Ceramic Fibres (RCF) exposure.
  • To highlight the diagnostic findings in a case of long-term RCF exposure.
  • To emphasize the need for specific medical surveillance protocols for RCF-exposed workers.

Main Methods:

  • Case study of a 45-year-old male with 20 years of RCF exposure in thermal insulation.
  • Occupational medical prophylaxis including X-ray and high-resolution computed tomography (HRCT).
  • Pulmonary function tests, scanning electron microscopy (SEM) with energy dispersive X-ray analysis (EDX), X-ray powder diffraction (XRD), and transmission electron microscopy (TEM).

Main Results:

  • Bilateral pleural thickening and pleural calcification with rounded atelectasis were detected via HRCT.
  • Pulmonary function tests revealed a restrictive lung pattern.
  • Material analysis confirmed the fibres as aluminium silicate, with both crystalline and amorphous forms present.

Conclusions:

  • Comprehensive lung function analysis is necessary for RCF-exposed workers.
  • Additional CT scans are recommended for those with restrictive lung disorders.
  • Medical surveillance for RCF exposure should align with guidelines for asbestos-exposed workers.