Severe post-COVID-19 costochondritis in children

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Reagan A Collins1, Nandini Ray1, Kelly Ratheal2

  • 1School of Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas.

Proceedings (Baylor University. Medical Center)
|December 30, 2021
PubMed

Insights

A rare long-term complication of COVID-19 in children is post-COVID-19 costochondritis (PCC). Colchicine effectively treated severe PCC in a pediatric case, offering a new therapeutic option.

Area of Science:

  • Pediatric Rheumatology
  • Infectious Diseases
  • Cardiology

Background:

  • COVID-19 can lead to various long-term health issues in children.
  • Musculoskeletal chest pain is an emerging post-COVID-19 complication.
  • Costochondritis, inflammation of cartilage in the rib cage, can cause severe chest pain.

Observation:

  • A pediatric patient presented with severe costochondritis unresponsive to standard treatments.
  • The patient had a history of COVID-19 infection several months prior.
  • This represents the first reported case of post-COVID-19 costochondritis (PCC) in a child.

Findings:

  • Successful management of severe PCC was achieved using colchicine.
  • Colchicine demonstrated efficacy in a case refractory to NSAIDs and steroids.
  • This case highlights a novel therapeutic approach for PCC.

Implications:

  • Colchicine should be considered for treating severe pediatric PCC unresponsive to conventional therapies.
  • Early recognition of PCC can prevent unnecessary interventions like steroid use and frequent ER visits.
  • This finding may reduce diagnostic delays and improve patient outcomes for post-COVID-19 inflammatory conditions.

Keywords:
COVID-19ColchicineSARS-CoV-2costochondritisnonsteroidal anti-inflammatory drugs

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