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Severity of precapillary pulmonary hypertension: Predictive factor
J A de Barros1, G Sant'Ana1, G Martins1
1Federal University of Paraná, Department of Internal Medicine, Cardiology and Pneumology Unit, Curitiba, Brazil.
Pulmonology
|December 31, 2021
Summary
The ratio of right ventricle to left ventricle (RV/LV) echocardiographic diastolic diameters can estimate the hemodynamic severity of precapillary pulmonary hypertension. An RV/LV ratio of 0.8 is the optimal cutoff for this assessment.
Area of Science:
- Cardiology
- Pulmonary Hypertension Research
- Echocardiography
Background:
- Pulmonary arterial hypertension (PAH) necessitates accurate risk assessment for prognosis and treatment.
- Current risk assessments can be improved by integrating right ventricle analysis.
- Precapillary pulmonary hypertension (PHprecapillary) requires precise hemodynamic severity estimation.
Purpose of the Study:
- To establish echocardiographic morphometric data of the right ventricle (RV) and its relationship with the left ventricle (LV).
- To correlate RV/LV echocardiographic data with hemodynamic parameters in PHprecapillary.
- To determine the utility of the RV/LV ratio in estimating hemodynamic severity.
Main Methods:
- Prospective, observational, cross-sectional study of 41 patients with PHprecapillary.
- Utilized echocardiographic studies and cardiac catheterization for data collection.
- Analyzed the ratio of right to left ventricle (RV/LV) echocardiographic diastolic diameters.
Main Results:
- The RV/LV echocardiographic diastolic diameter ratio correlated significantly with pulmonary arterial pressures.
- An RV/LV ratio cutoff of 0.8 demonstrated high sensitivity and specificity for systolic and mean pulmonary pressures.
- Significant correlations were found between RV/LV ratio and systolic pressure, mean pressure, transpulmonary pressure gradient, and pulmonary vascular resistance.
Conclusions:
- The RV/LV echocardiographic diastolic diameter ratio is a valuable tool for estimating hemodynamic severity in PHprecapillary.
- An RV/LV ratio of 0.8 serves as an effective cutoff for this hemodynamic assessment.
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