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Graves' disease following administration of second dose of SARS-CoV-2 vaccine
Timothy James Goblirsch1, Ambika E Paulson2, Gerti Tashko3
1Medicine, Georgetown University School of Medicine, Washington, DC, USA tjg58@georgetown.edu.
Abstract:
The SARS-CoV-2 vaccines have had an overwhelming success in curbing the COVID-19 global pandemic, accounting for countless lives saved. Adverse reactions are inevitable, given the vast scale of vaccination required to mitigate future surges of COVID-19. Hyperthyroid disorders have been reported as potential adverse reactions to SARS-CoV-2 vaccines in two patients with Graves' disease and a group of adults with subacute thyroiditis occurring in young women healthcare workers. We report a case of clinical Graves' disease in a woman with a previously stable multinodular goitre that occurred 14 days following her second dose of Pfizer-BioNTech SARS-CoV-2 vaccine.
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