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Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults
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Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults

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Assessment of bronchodilator response by forced oscillation technique in a preterm infant with evolving

Camilla Rigotti1, Emanuela Zannin1, Abedulrhman S Abdelfattah1,2

  • 1Neonatal Intensive Care Unit, Fondazione Monza e Brianza per il Bambino e la sua Mamma (MBBM), Monza, Italy.

Pediatric Pulmonology
|December 31, 2021
PubMed

Insights

Forced oscillation technique (FOT) can identify preterm infants who may benefit from inhaled bronchodilators for bronchopulmonary dysplasia. This noninvasive method assesses airway obstruction reversibility, guiding optimal treatment timing and patient selection.

Area of Science:

  • Neonatal Medicine
  • Pediatric Pulmonology
  • Respiratory Physiology

Background:

  • Bronchopulmonary dysplasia (BPD) is a common complication in preterm infants.
  • Inhaled bronchodilators are frequently used, but patient selection and treatment timing remain unclear.
  • Assessing airway obstruction reversibility in infants is challenging due to cooperation requirements.

Observation:

  • The forced oscillation technique (FOT) is a noninvasive method to assess lung mechanics.
  • FOT has demonstrated sensitivity to airway obstruction reversibility in children and adults.
  • FOT requires no patient cooperation, making it suitable for infants.

Findings:

  • This case report introduces the use of FOT in preterm infants with BPD.
  • FOT was utilized to assess airway obstruction reversibility in this population.
  • The study suggests FOT can inform clinical benefit from bronchodilator therapy.

Implications:

  • FOT shows potential as a valuable tool for guiding bronchodilator treatment in preterm infants with BPD.
  • This technique may help personalize treatment decisions, optimizing outcomes.
  • Further research is warranted to validate FOT's role in clinical practice.

Keywords:
bronchopulmonary dysplasia (BPD)infant pulmonary functionneonatal pulmonary medicinepulmonary function testing (PFT)

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