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Inter-observer variation in target delineation and dose trade-off for radiotherapy of paediatric ependymoma

Laura Toussaint1, Petter Brandal2,3, Anna Embring4

  • 1Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.

Acta Oncologica (Stockholm, Sweden)
|December 31, 2021
PubMed
Abstract

No abstract available in PubMed .

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Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
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