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A Murine Model of Hemodialysis Access-Related Hand Dysfunction
Published on: May 31, 2022
Hand Grip Strength in Patients on Hemodialysis: An Observational Study
M Tsekoura1, G Drousiotis2, M Avgeri2
1Department of Physiotherapy, School of Health Rehabilitation Sciences, University of Patras, Patras, Greece. mariatsekoura@hotmail.com.
Abstract:
The objective of this study is to evaluate hand grip strength (HGS) in patients on hemodialysis and to investigate associated factors (anthropometric characteristics, body composition, and quality of life). An observational study of 60 patients in one hemodialysis center (Filoxenia Dialysis center, Aigio, Greece) was conducted. Measures of HGS were performed with a hydraulic dynamometer (Saehan Corporation, South Korea) on the non-fistula hand before the hemodialysis session. Demographic and clinical data (dialysis start date, comorbidities, and etiology of chronic kidney disease) were collected from the patients' medical charts. Body composition was determined by bioelectrical impedance analysis and calf circumference with inelastic tape. Quality of life was assessed via EuroQol (EQ-5D) questionnaire. Descriptive statistics were used for data analyses. The association between variables was calculated using Pearson's r correlation coefficients. The experimental design of this study was approved by the Ethics Committee of the Technological Educational Institute of Western Greece. A total of 54 patients (71.2 ± 10.9 years old, 24% diabetic, BMI of 26.34 ± 5.2) participated in this study (response rate 90%). The average duration of hemodialysis was 4.29 ± 6.36 years. The maximum HGS in the dominant was 19.19 ± 12.1 kg (female 12.04 ± 7.26 kg, male 21.82 ± 12.52 kg, p < 0.001). HGS was significantly correlated with age (r = 0.5; p < 0.001) and moderately correlated with gender (r = 0.36; p = 0.008), BMI (r = 0.3; p = 0.03), calf circumference (r = 0.4; p = 0.03), and quality of life (r = 0.37; p = 0.006). The use of hand-held dynamometry could be a fundamental element of the physical examination of patients receiving hemodialysis, particularly if they are older adults.
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Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...

