Recapitulating human myogenesis ex vivo using human pluripotent stem cells.

Peggie Chien1, Haibin Xi1, April D Pyle1

  • 1Department of Microbiology, Immunology and Molecular Genetics, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, Molecular Biology Institute, University of California, Los Angeles, CA, 90095, USA.

Summary

Human pluripotent stem cells (hPSCs) model human muscle development for disease research and therapies. Derived muscle stem cells offer potential cell-based treatments for skeletal muscle wasting conditions.