[Histiocytosis X: scintigraphic and roentgenologic findings]

The aim of this study was to compare the roentgenological and scintigraphic osseous changes in 25 resp. 18 patients with histiocytosis X and to analyse them. In particular, it was also interesting to discuss the divergent reports in the literature in respect of scintigraphic storage behaviour. In all the patients examined before initiation of therapy (39 osseous foci) high activities were found scintigraphically. The extension of the scintigraphically active zone was much greater than the corresponding translucencies on the x-ray film. On the other hand, patients after therapy still showed foci on the x-ray film whereas the scan had already become inactive. This striking discrepancy between scan findings before and after therapy could be one of the reasons for divergent literature reports on this problem.