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Updated: Oct 8, 2025

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Implementation and outcomes of a standard dose dextrose gel protocol for management of transient neonatal
Purnahamsi Desai1,2, Sourabh Verma3,4, Sweta Bhargava5
1New York University Grossman School of Medicine, New York, NY, USA. Purnahamsi.desai@nyulangone.org.
Objective:
The use of oral dextrose gel (DG) reduces IV dextrose use. Prior studies used weight-based dosing (WD), though barriers exist, and are mitigated using standard dosing (SD). Our outcomes include IV dextrose use, NICU admissions, breastfeeding, adverse events, and assessment of WD vs SD.
Study Design:
Retrospective chart review comparing pre-DG, WD, and SD in 16490 newborns (1329 hypoglycemic) ≥ 35 weeks admitted to the nursery over 3 years.
Results:
There was reduction in IV dextrose use 10.9% vs 6.5% (p = 0.004) and NICU admissions 27.9% vs 16.1% (p < 0.001) associated with DG use, and increased rate of breastfed infants 33.8% vs 43.5% (p = 0.001), with no difference between WD and SD. No difference noted in adverse events across the study period.
Conclusions:
DG utilization is associated with reduced IV dextrose use, NICU admissions, and improved breastfeeding rates without changes in adverse events. We offer SD as a safe alternative to WD.
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