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Updated: Oct 8, 2025
An Immature Murine Model of Reversible Unilateral Ureteral Obstruction
Published on: April 4, 2025
Quasi-linear viscoelastic behavior of fresh porcine ureter
Jianli Wang1, Jiawei Chen1, Xincheng Gao1
1Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, HB, China.
Purpose:
To evaluate the viscoelastic properties of the fresh porcine ureter. Prove the QLV theory can sufficiently model the stress relaxation function of porcine ureters, and determine the QLV model constants which may provide insight into the synthesis of ureteral scaffolds with biomimetic viscoelastic properties in tissue engineering.
Methods:
Hysteresis tests were applied to study the differences in dissipated energy ratio for each different strain group. In stress relaxation tests, samples were sub-grouped and quickly ramping up to 5%, 20%, and 30% strain in each group and gradually relaxed to a corresponding level. Bringing together the quasi-linear viscoelasticity (QLV) theory and stress relaxation function to determine the eight constants of the ureteral tissue, and fitting the raw data with the model via MATLAB.
Results:
The hysteresis response measurement results revealed that the porcine ureter was a highly dissipative material and there were differences between toe and linear region in stress-stain curve. The stress relaxation results revealed ureters responded with time-dependent decay of stress. The eight constants of the ureteral QLV model were determined for three different strain groups, and we proved that the QLV model can sufficiently adapt the experimental data of the ureter stress relaxation.
Conclusion:
This study investigated the time-dependent properties of the porcine ureter, and demonstrated the QLV theory could be used to evaluate the viscoelastic properties of the porcine ureteral tissue.
