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[Relative factors analysis of visual field defect in advanced primary glaucoma]
H L Huang1, K D Wang1, X H Sun1
1Department of Ophthalmology, Eye & ENT Hospital of Fudan University, NHC Key Laboratory of Myopia (Fudan University), Laboratory of Myopia, Chinese Academy of Medical Science, Shanghai 200031, China.
[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology
|January 4, 2022
Summary
Chronic primary angle-closure glaucoma (CPACG), elevated peak intraocular pressure (IOP), and high myopia are key factors in the progression of temporal peripheral visual field defects in advanced primary glaucoma patients.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Visual Field Defect Analysis
Background:
- Advanced primary glaucoma can lead to significant visual field defects.
- Understanding the specific factors contributing to different types of visual field loss is crucial for patient management.
Purpose of the Study:
- To identify the relative factors associated with temporal peripheral visual field defects in advanced primary glaucoma.
- To compare these factors with those affecting central visual field defects.
Main Methods:
- A retrospective case-control study involving 287 patients with advanced primary glaucoma.
- Patients were categorized into central and temporal peripheral visual field defect groups.
- Statistical analyses included Chi-square tests, independent t-tests, and multivariate logistic regression.
Main Results:
- Higher peak intraocular pressure (IOP), chronic primary angle-closure glaucoma (CPACG), and high myopia were significantly associated with temporal peripheral visual field defects.
- Multivariate analysis confirmed CPACG (OR=2.021), higher peak IOP (OR=1.128), and high myopia (OR=5.090) as risk factors for temporal field progression.
Conclusions:
- CPACG, elevated peak IOP, and high myopia are significant risk factors contributing to the progression of temporal peripheral visual field loss in advanced primary glaucoma.
- These findings highlight specific risk profiles for different visual field defect patterns in glaucoma.
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