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Updated: Oct 8, 2025

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
Mucopolysaccharidosis Type I Diagnosed by Aortic and Mitral Valve Replacement
Dalton J Sherwood1, Michael C Adams2, Anthony J Mazzella3
1Department of Medicine, University of North Carolina Hospitals, Chapel Hill, North Carolina, USA.
Abstract:
A 32-year-old developmentally delayed man presenting with dyspnea was found to have severe aortic and mitral valve stenosis. After double valve replacement, unique histologic findings prompted a genetics evaluation, ultimately leading to the diagnosis of mucopolysaccharidosis type I, a rare lysosomal storage disorder with high rates of cardiac manifestations. (Level of Difficulty: Advanced.).
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