Related Experiment Video
Updated: Oct 7, 2025

06:15
Tumor Treating Field Therapy in Combination with Bevacizumab for the Treatment of Recurrent Glioblastoma
Published on: October 27, 2014
27.6K
A Case Study Using Papaya Leaf Extract to Reverse Chemotherapy-Induced Thrombocytopenia in a GBM Patient
Abigail Koehler1, Rohan Rao1, Yehudit Rothman1
1University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Integrative Cancer Therapies
|January 5, 2022
Summary
Carica papaya leaf extract (CPLE) may help increase low platelet counts in patients with chemotherapy-induced thrombocytopenia (CIT). A patient
Area of Science:
- Oncology
- Hematology
- Pharmacology
Background:
- Chemotherapy-induced thrombocytopenia (CIT) is a serious complication of cancer treatment.
- Low platelet counts increase bleeding risk and complicate cancer management.
- Current treatments for CIT have limitations and risks.
Purpose of the Study:
- To report the novel use of Carica papaya leaf extract (CPLE) for chemotherapy-induced thrombocytopenia.
- To evaluate the efficacy of CPLE in a patient with significantly reduced platelet counts.
Main Methods:
- A patient with CIT was treated with 1 tablespoon of CPLE twice daily.
- Platelet counts were monitored before and after CPLE administration.
Main Results:
- The patient's platelet count increased from less than 10,000/µL to 113,000/µL after CPLE treatment.
- CPLE therapy was associated with a significant rebound in platelet levels.
Conclusions:
- CPLE shows potential as a treatment for chemotherapy-induced thrombocytopenia.
- Further research into CPLE for refractory or non-traditional thrombocytopenia cases is warranted.

