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Updated: Oct 7, 2025

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
Preterm infant with diprosopus and holoprosencephaly
Nitya M Nair1, Daniel T Swarr2,3, Maria E Barnes-Davis2,3
1Division of Neonatology Department of Pediatrics Emory University School of Medicine and Children's Healthcare of Atlanta Atlanta Georgia USA.
Abstract:
Diprosopus is an extremely rare congenital anomaly involving craniofacial duplication. The etiology and pathophysiology remain unknown, and no genetic mutations have been definitively associated with the condition. This case describes an infant born at 27-weeks completed gestation with multiple congenital anomalies including diprosopus and discusses the implications of prenatal diagnosis.
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