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Updated: Oct 7, 2025
Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria
Published on: May 8, 2013
Methicillin-Resistant and Methicillin-Sensitive Staphylococcus aureus Hospitalizations: National Inpatient Sample,
Eili Y Klein1,2, Xianming Zhu3, Molly Petersen3
1Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Abstract:
Data from the National Inpatient Sample demonstrate that methicillin-resistant Staphylococcus aureus (MRSA)-related septicemia hospitalizations increased from 1.67 (95% CI, 1.63-1.72) to 1.94 (95% CI, 1.88-2.00; P trend < .001) discharges per 1000 hospitalizations between 2016 and 2019. Regionally, the trends were similar. Rates of MSSA-related septicemia and pneumonia hospitalizations also increased significantly over this time period.
Insights
Hospitalizations for methicillin-resistant Staphylococcus aureus (MRSA) septicemia rose significantly between 2016 and 2019. Methicillin-susceptible Staphylococcus aureus (MSSA) septicemia and pneumonia hospitalizations also saw notable increases during this period.
Area of Science:
- Infectious Diseases
- Epidemiology
- Public Health
Background:
- Methicillin-resistant Staphylococcus aureus (MRSA) is a significant cause of healthcare-associated infections.
- Septicemia and pneumonia are serious conditions that can lead to increased hospitalizations and mortality.
- Understanding trends in MRSA and MSSA hospitalizations is crucial for public health interventions.
Purpose of the Study:
- To analyze trends in hospitalizations related to MRSA and MSSA septicemia and pneumonia.
- To assess changes in hospitalization rates between 2016 and 2019.
- To identify regional variations in these trends.
Main Methods:
- Utilized data from the National Inpatient Sample.
- Analyzed hospitalization rates per 1000 discharges.
- Examined trends over a four-year period (2016-2019).
Main Results:
- MRSA-related septicemia hospitalizations increased from 1.67 to 1.94 per 1000 hospitalizations (P < .001).
- Similar upward trends were observed regionally.
- Hospitalizations for MSSA-related septicemia and pneumonia also increased significantly.
Conclusions:
- There has been a significant increase in MRSA and MSSA-related hospitalizations for septicemia and pneumonia.
- These trends highlight a growing burden of Staphylococcus aureus infections.
- Continued surveillance and targeted interventions are necessary to combat these infections.
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