Trends and Treatment of Sub-Acute Sclerosing Panencephalitis: An Updated Review

Shahzeb Ali Memon1, Syed Shabbir Afzal2, Alaa Tukruna3

  • 1Dow Medical College, Karachi, Sindh, Pakistan.

Global Pediatric Health
|January 6, 2022
PubMed

Insights

Measles (Rubeola virus) is a contagious disease with severe outcomes. This review assesses current literature on management and treatment options for this serious, though currently incurable, illness.

Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Background:

  • Measles, caused by the Rubeola virus, is highly contagious and can lead to fatal complications like sub-acute sclerosing pan-encephalitis.
  • Suboptimal vaccination programs in underdeveloped regions contribute to ongoing measles outbreaks and severe sequelae.
  • Despite various management strategies, measles remains an incurable disease.

Purpose of the Study:

  • To review existing literature on measles (Rubeola virus) infection.
  • To discuss potential treatment modalities for measles.
  • To highlight the impact of vaccination challenges on measles prevalence.

Main Methods:

  • Literature review of previous studies on measles.
  • Assessment of documented treatment and management strategies.
  • Analysis of factors contributing to measles outbreaks.

Main Results:

  • Measles presents with symptoms like fever, cough, conjunctivitis, and runny nose.
  • Severe complications, including fatal sub-acute sclerosing pan-encephalitis, can arise from measles infection.
  • Challenges in global vaccination programs exacerbate measles incidence.

Conclusions:

  • Measles (Rubeola virus) poses a significant global health threat due to its contagiousness and potential for severe complications.
  • Effective management and treatment strategies are crucial, despite the current lack of a cure.
  • Improving global immunization programs is vital to control measles outbreaks and reduce associated mortality and morbidity.

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