Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Trimethoprim-sulfamethoxazole.

F R Cockerill1, R S Edson

  • 1Division of Infectious Diseases and Internal Medicine, Mayo Clinic Jacksonville, Florida.

Mayo Clinic Proceedings
|October 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Inhibition controls for qualitative real-time PCR assays: are they necessary for all specimen matrices?

Journal of clinical microbiology·2014
Same author

Multiplex Polymerase Chain Reaction Detection of vanA, vanB, vanC-1, and vanC-2/3 Genes in Enterococci.

Methods in molecular medicine·2011
Same author

Tuberculosis attributed to household contacts in the Philippines.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2009
Same author

Real-time PCR in clinical microbiology: applications for routine laboratory testing.

Clinical microbiology reviews·2006
Same author

Optimal testing parameters for blood cultures.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2004
Same author

Comparison of the Roche LightCycler vanA/vanB detection assay and culture for detection of vancomycin-resistant enterococci from perianal swabs.

Journal of clinical microbiology·2004
Same journal

37-Year-Old Woman With Jaundice.

Mayo Clinic proceedings·2026
Same journal

34-Year-Old Woman With An Unidentified Overdose.

Mayo Clinic proceedings·2026
Same journal

Use of Bronchoscopic Cryobiopsy in Evaluating Interstitial Lung Disease: Radiologic Predictors of Diagnostic Yield and Safety.

Mayo Clinic proceedings·2026
Same journal

Advancing Pulmonary Fibrosis Care: Integrating Genomic Insights Into Clinical Practice.

Mayo Clinic proceedings·2026
Same journal

RAAS Inhibition in the ICU: Stop, Continue, or Restart?

Mayo Clinic proceedings·2026
Same journal

Chronic Kidney Disease-In the Limelight, July 2026.

Mayo Clinic proceedings·2026
See all related articles

Trimethoprim-sulfamethoxazole effectively treats various bacterial infections, including genitourinary, respiratory, and gastrointestinal. Dosage adjustment is crucial for patients with reduced kidney function.

Area of Science:

  • Pharmacology
  • Infectious Diseases
  • Microbiology

Background:

  • Trimethoprim-sulfamethoxazole is a widely used antimicrobial combination.
  • It exhibits in vitro activity against diverse gram-positive and gram-negative bacteria.

Purpose of the Study:

  • To review the clinical utility of trimethoprim-sulfamethoxazole.
  • To highlight its applications in treating and preventing specific infections.
  • To discuss its role in managing Nocardia asteroides infections and Pneumocystis carinii pneumonia.

Main Methods:

  • Clinical efficacy review.
  • Pharmacokinetic and excretion profile analysis.
  • Dosage adjustment guidelines for renal impairment.

Main Results:

Related Experiment Videos

  • Effective for genitourinary, respiratory, and gastrointestinal infections.
  • Preferred agent for Pneumocystis carinii pneumonia and Nocardia asteroides infections.
  • Relatively safe in non-AIDS patients; available in oral and IV forms.

Conclusions:

  • Trimethoprim-sulfamethoxazole is a versatile antimicrobial for various infections.
  • Renal function significantly impacts drug excretion, necessitating dosage adjustments.
  • Essential drug for specific opportunistic infections, particularly in immunocompromised individuals.