Clinical acceptance of deep learning reconstruction for abdominal CT imaging: objective and subjective image quality...

To evaluate the image quality and clinical acceptance of a deep learning reconstruction (DLR) algorithm compared to traditional iterative reconstruction (IR) algorithms.

CT acquisitions were performed with two phantoms and a total of nine dose levels. Images were reconstructed with two types of IR algorithms, DLR and filtered-back projection. Spatial resolution, image texture, mean noise value, and objective and subjective low-contrast detectability were compared. Ten senior radiologists evaluated the clinical acceptance of these algorithms by scoring ten CT exams reconstructed with the DLR and IR algorithms evaluated.

Compared to MBIR, DLR yielded a lower noise and a higher low-contrast detectability index at low doses (CTDI_vol ≤ 2.2 and ≤ 4.5 mGy, respectively). Spatial resolution and detectability at higher doses were better with MBIR. Compared to HIR, DLR yielded a higher spatial resolution, a lower noise, and a higher detectability index. Despite these differences in algorithm performance, significant differences in subjective low-contrast performance were not found (p ≥ 0.005). DLR texture was finer than that of MBIR and closer to that of HIR. Radiologists preferred DLR images for all criteria assessed (p < 0.0001), whereas MBIR was rated worse than HIR (p < 0.0001) in all criteria evaluated, except for noise (p = 0.044). DLR reconstruction time was 12 times faster than that of MBIR.

DLR yielded a gain in objective detection and noise at lower dose levels with the best clinical acceptance among the evaluated reconstruction algorithms.

• DLR yielded improved objective low-contrast detection and noise at lower dose levels. • Despite the differences in objective detectability among the algorithms evaluated, there were no differences in subjective detectability. • DLR presented significantly higher clinical acceptability scores compared to MBIR and HIR.