Eroding norms over release of self-spreading viruses
Filippa Lentzos1, Edward P Rybicki2, Margret Engelhard3
1Departments of Global Health and Social Medicine and of War Studies, King's College London, London, UK.
Science (New York, N.Y.)
|January 6, 2022
Summary
Research into self-spreading viruses modified in laboratories has not yet shown clear benefits. This risky scientific endeavor requires further investigation into potential upsides and safety concerns.
Area of Science:
- Virology
- Genetic Engineering
- Biosafety
Background:
- Self-spreading viruses (SSVs) are engineered to transmit efficiently between hosts.
- Concerns exist regarding the potential for unintended consequences and ecological disruption.
- Current research focuses on understanding transmission dynamics and containment strategies.
Purpose of the Study:
- To evaluate the potential benefits of lab-modified self-spreading viruses.
- To identify credible pathways for advantageous applications.
- To assess the risks associated with developing self-spreading virus technologies.
Main Methods:
- Review of existing literature on SSV research.
- Analysis of proposed applications and their feasibility.
- Risk assessment of potential ecological and public health impacts.
Main Results:
- No clear or credible upsides have been identified in current research.
- Potential risks associated with uncontrolled spread and ecological imbalance are significant.
- The development of safe and beneficial SSVs remains a major challenge.
Conclusions:
- Lab-modified self-spreading viruses currently lack demonstrated benefits.
- Significant biosafety and biosecurity concerns warrant extreme caution.
- Further research must prioritize safety and clearly defined beneficial applications before proceeding.
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