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Updated: Oct 7, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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YAP1 and PRDM14 converge to promote cell survival and tumorigenesis

Miju Kim1, Seav Huong Ly1, Yingtian Xie2

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

Developmental Cell
|January 6, 2022
PubMed

Keywords:
Hippo pathwayKRASPRDM14YAP1colon canceroncogene addictionresistance

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