Oral Aversion in Infants With Congenital Heart Disease: A Single-Center Retrospective Cohort Study

Stephanie A Goldstein1, Kimberly J Watkins2, Ray E Lowery3

  • 1Division of Pediatric Critical Care, Department of Pediatrics, University of Utah, Primary Children's Hospital, Salt Lake City, UT.

Insights

Oral aversion (OA) affects nearly a quarter of neonates one year after heart surgery. Early oral feeding at discharge may reduce the risk of developing OA in infants.

Area of Science:

  • Pediatric Cardiology
  • Neonatal Surgery
  • Feeding Disorders

Background:

  • Neonates undergoing cardiac surgery face risks, including oral aversion (OA).
  • Oral aversion's long-term impact beyond initial hospitalization is not well-documented.
  • Understanding OA prevalence is crucial for affected infants and their families.

Purpose of the Study:

  • To determine the prevalence of oral aversion (OA) at one year of age in neonates who underwent cardiopulmonary bypass (CPB) surgery.
  • To identify risk factors associated with OA in this vulnerable population.
  • To explore the relationship between feeding practices and OA development.

Main Methods:

  • A retrospective cohort study was conducted at a single quaternary care hospital.
  • 157 neonates who underwent CPB surgery between 2014 and 2017 with one-year follow-up data were analyzed.
  • Feeding experts reviewed medical records to diagnose OA, with inter-rater reliability assessed.

Main Results:

  • Oral aversion (OA) was present in 23.6% of patients at one year; an additional 18.5% had other feeding difficulties.
  • Factors associated with OA included longer ICU stays, mechanical ventilation, nil per os days, and delayed oral feeding initiation.
  • Infants with any oral intake at discharge had significantly lower odds of developing OA at one year.

Conclusions:

  • Oral aversion and feeding difficulties are common sequelae in neonates post-cardiopulmonary bypass surgery.
  • Delayed initiation of oral feeding appears to be a modifiable risk factor for OA.
  • Interventions promoting early oral feeding may improve long-term functional outcomes for these infants.
Abstract

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