Acute and Subclinical Myocardial Injury in COVID-19
Valentina L Crudo1, Ahmed I Ahmed1, Eilidh L Cowan1
1Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas, US.
Insights
Coronavirus disease 2019 (COVID-19) causes widespread myocardial injury in patients, impacting those with and without prior heart conditions. This review examines the latest evidence on the frequency and causes of heart damage in COVID-19 patients.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic has caused millions of deaths globally.
- Cardiovascular complications are a significant concern in hospitalized COVID-19 patients.
- Myocardial injury, ranging from mild to severe, is frequently observed in these patients.
Purpose of the Study:
- To review the latest evidence on the prevalence of myocardial injury in COVID-19.
- To explore the potential etiologies of acute and subclinical myocardial injury in COVID-19 patients.
- To consolidate current understanding of cardiovascular manifestations of COVID-19.
Main Methods:
- Systematic review of recent scientific literature.
- Analysis of clinical data and case studies on COVID-19 patients.
- Synthesis of findings on myocardial injury markers and outcomes.
Main Results:
- COVID-19 is associated with a high incidence of myocardial injury, including biomarker elevations, myocardial infarction, and arrhythmias.
- Both patients with and without pre-existing cardiovascular disease are susceptible to COVID-19-related heart damage.
- Subclinical myocardial injury is common and may precede overt cardiac events.
Conclusions:
- Myocardial injury is a critical complication of COVID-19, contributing to morbidity and mortality.
- Understanding the mechanisms of COVID-19-induced heart damage is crucial for patient management.
- Further research is needed to elucidate the long-term cardiovascular consequences of COVID-19.
Abstract:
Coronavirus disease 2019 (COVID-19) is a global pandemic that, at the time of this writing, has led to 178,000,000 cases worldwide and more than 3,875,000 deaths. Cardiovascular complications of COVID-19 have become the focus of investigation after many hospitalized COVID-19 patients-with or without established cardiovascular disease-incurred clinical or subclinical myocardial injury, including isolated biomarker elevations, myocardial infarction, arrhythmia, heart failure, myocarditis, and cardiogenic shock. In this review, we highlight the most recent evidence of the prevalence and potential etiologies of acute and subclinical myocardial injury in COVID-19 patients.
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