Acute and Subclinical Myocardial Injury in COVID-19

Valentina L Crudo1, Ahmed I Ahmed1, Eilidh L Cowan1

  • 1Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas, US.

Insights

Coronavirus disease 2019 (COVID-19) causes widespread myocardial injury in patients, impacting those with and without prior heart conditions. This review examines the latest evidence on the frequency and causes of heart damage in COVID-19 patients.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • The COVID-19 pandemic has caused millions of deaths globally.
  • Cardiovascular complications are a significant concern in hospitalized COVID-19 patients.
  • Myocardial injury, ranging from mild to severe, is frequently observed in these patients.

Purpose of the Study:

  • To review the latest evidence on the prevalence of myocardial injury in COVID-19.
  • To explore the potential etiologies of acute and subclinical myocardial injury in COVID-19 patients.
  • To consolidate current understanding of cardiovascular manifestations of COVID-19.

Main Methods:

  • Systematic review of recent scientific literature.
  • Analysis of clinical data and case studies on COVID-19 patients.
  • Synthesis of findings on myocardial injury markers and outcomes.

Main Results:

  • COVID-19 is associated with a high incidence of myocardial injury, including biomarker elevations, myocardial infarction, and arrhythmias.
  • Both patients with and without pre-existing cardiovascular disease are susceptible to COVID-19-related heart damage.
  • Subclinical myocardial injury is common and may precede overt cardiac events.

Conclusions:

  • Myocardial injury is a critical complication of COVID-19, contributing to morbidity and mortality.
  • Understanding the mechanisms of COVID-19-induced heart damage is crucial for patient management.
  • Further research is needed to elucidate the long-term cardiovascular consequences of COVID-19.

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