Related Experiment Video
Updated: Oct 7, 2025
04:53
Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks
Published on: May 26, 2023
1.4K
Metal-Organic Frameworks and Their Composites Towards Biomedical Applications
Yana Ma1,2, Xianglong Qu3, Cui Liu1,2
1School of Basic Medical Sciences, Xi'an Key Laboratory of Immune Related Diseases, Xi'an Jiaotong University, Xi'an, China.
Frontiers in Molecular Biosciences
|January 7, 2022
Summary
Metal-organic frameworks (MOFs) and composites show promise in nanomedicine for drug delivery, therapy, and imaging. This review covers MOF applications, functionalities, and future prospects in the field.
Area of Science:
- Materials Science
- Nanotechnology
- Biomedical Engineering
Background:
- Metal-organic frameworks (MOFs) possess unique properties like high cargo capacity, biodegradability, and tunable structures.
- These characteristics make MOFs and their composites attractive for advanced applications.
Purpose of the Study:
- To review the application strategies of MOFs and their composites in nanomedicine.
- To highlight their diverse functions, including drug delivery, disease treatment, and medical imaging.
Main Methods:
- Literature review of MOF applications in nanomedicine.
- Analysis of MOF derivatives and their functional modifications.
- Discussion of targeting strategies, biomimetic modifications, and responsive moieties.
Main Results:
- MOFs are versatile platforms for drug delivery systems, therapeutic agents, and imaging contrast agents.
- MOF derivatives and functional decorations enhance their efficacy and targeting capabilities.
- MOFs function as sensor nanoreactors for diagnostic and therapeutic purposes.
Conclusions:
- MOFs and their composites offer significant potential in nanomedicine due to their adaptable nature.
- Further research into MOF functionalities and overcoming current challenges will drive future applications in healthcare.
