Protein nanoparticles directed cancer imaging and therapy

Area of Science:

• Biomaterials Science
• Nanotechnology
• Oncology

Background:

• Protein nanoparticles are advantageous drug delivery carriers due to their biocompatibility and biodegradability.
• They offer solutions to the poor biocompatibility issues associated with inorganic nanocarriers.
• Their surface properties facilitate drug loading and modification for advanced applications.

Purpose of the Study:

• To review representative protein nanoparticles for cancer theranostics.
• To describe common preparation methods for these nanoparticles.
• To critically analyze their use in improving cancer imaging and therapy.

Main Methods:

• Literature review of protein nanoparticles in cancer theranostics.
• Categorization of nanoparticles including virus-like particles, albumin, silk, and ferritin nanoparticles.
• Analysis of preparation techniques and theranostic applications.

Main Results:

• Protein nanoparticles exhibit excellent biocompatibility and biodegradability.
• Various types like virus-like particles, albumin, silk, and ferritin nanoparticles are suitable for cancer theranostics.
• These nanoparticles can be functionalized for enhanced drug delivery, imaging, and therapeutic outcomes.

Conclusions:

• Protein nanoparticles represent a promising platform for cancer theranostics.
• Their tunable properties allow for multifunctional theranostic systems.
• Further research into protein nanoparticle applications can significantly advance cancer treatment and diagnosis.