Aspirin prescribing pattern and guidelines-adherence evaluation for primary prevention of cardiovascular diseases at

Salman Almalki1, Abdulaziz Alhossan2,3, Bashayer Alrumayyan2

  • 1College of Pharmacy, Riyadh Elm University, Riyadh, Saudi Arabia.

Insights

Many patients inappropriately use aspirin for cardiovascular disease prevention. This study found significant deviations from guidelines, highlighting a need for better education and adherence among healthcare providers to prevent complications.

Area of Science:

  • Cardiology
  • Pharmacology
  • Public Health

Background:

  • Cardiovascular diseases (CVDs) remain a leading cause of mortality globally.
  • Aspirin is widely used for primary CVD prevention, but its use must align with established guidelines.
  • Inappropriate aspirin prescribing can lead to adverse events without proven benefit.

Purpose of the Study:

  • To evaluate aspirin prescribing patterns for primary CVD prevention.
  • To assess adherence to international guidelines for aspirin use in a teaching hospital setting.
  • To identify potential overuse and underuse of aspirin in patient populations.

Main Methods:

  • Retrospective analysis of 816 patients receiving aspirin for primary CVD prevention.
  • Assessment of patient demographics, comorbidities (diabetes, hypertension, dyslipidemia), and BMI.
  • Application of aspirin candidacy calculations based on international recommendations.

Main Results:

  • A significant proportion of patients (23%) were on aspirin without clear indication.
  • Only 6% of patients met criteria for high recommendation, while 49% had reasonable recommendation.
  • The majority of patients were obese (85.78%) and had multiple comorbidities.

Conclusions:

  • Current aspirin prescribing for primary CVD prevention in the studied population deviates significantly from international guidelines.
  • There is a notable prevalence of inappropriate aspirin use, necessitating improved adherence and education.
  • Further research is crucial to understand prescribing patterns and mitigate aspirin-associated risks.

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