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Related Concept Videos

Stress: General Loading Conditions01:15

Stress: General Loading Conditions

395
To grasp the intricacy of real-world conditions where multiple loads are applied simultaneously to a structure, one might visualize a section passing through a specific point within a body, aligned parallel to the xy plane. This section is subjected to various forces, including original loads, normal forces, and shearing forces.
The shearing force, possessing potential directionality within the plane of the section, is simplified into two component forces running parallel to the x and y axes....
395

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Co-localizing Kelvin Probe Force Microscopy with Other Microscopies and Spectroscopies: Selected Applications in Corrosion Characterization of Alloys
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Biocompatibility and Microstructure-Based Stress Analyses of TiNbZrTa Composite Films.

Bo-Wei Lai1, Yin-Yu Chang2, Tzong-Ming Shieh1

  • 1School of Dentistry, China Medical University, Taichung 404, Taiwan.

Materials (Basel, Switzerland)
|January 11, 2022
PubMed
Summary

This study enhanced titanium implants with TiNbZrTa coatings, showing excellent biocompatibility and reduced stress concentration for improved implant longevity. These advanced coatings show promise for future biomedical applications.

Keywords:
RT-qPCR analysisTiNbZrTiNbZrTaTiNbZrTa(N)TiNbZrTa(N)-O coatingsTiNbZrTa-Obone differentiationcell morphologycell viabilitycytotoxicitymicrostructure stress analysis

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Area of Science:

  • Biomaterials Science
  • Materials Engineering
  • Orthopedic and Dental Implants

Background:

  • Orthopedic and dental implants improve patient quality of life but face long-term loosening and complications.
  • Surface modification of Ti-6Al-4V aims to enhance structural strength and biocompatibility.

Purpose of the Study:

  • To deposit titanium (Ti)-niobium (Nb)-zirconium (Zr)-tantalum (Ta) alloys on Ti-6Al-4V surfaces.
  • To evaluate the biocompatibility and structural integrity of novel alloy coatings for potential implant applications.

Main Methods:

  • Cathodic arc evaporation used to create TiNbZr and TiNbZrTa coatings, with nitrogen addition for TiNbZrTa(N) films.
  • Biological assessments included cytotoxicity, cell viability (MG-63, L-929), cell morphology, and osteogenic differentiation.
  • Finite element analysis (FEA) evaluated stress distribution in 3D models of coated and uncoated samples.

Main Results:

  • Surface treatments showed no significant cytotoxicity and promoted L-929 cell activity, with good cell attachment observed for both cell types.
  • Osteogenic differentiation was unaffected, but gene expression analysis indicated improved performance of L-929 cells for collagen and fibronectin.
  • FEA confirmed that the TiNb interlayer effectively reduced stress concentration within the layered coatings.

Conclusions:

  • TiNbZrTa series films exhibit excellent biocompatibility with titanium alloys, especially for soft tissue cells.
  • The TiNb interlayer enhances the suitability of TiNbZrTa films for biomedical implants by reducing stress concentration.