Electrochemical Signal Substance for Multiplexed Immunosensing Interface Construction: A Mini Review

Area of Science:

• Electrochemistry
• Biosensor Technology
• Cancer Diagnostics

Background:

• Multiplexed electrochemical immunosensing interfaces require effective signal substance labeling for enhanced cancer diagnosis specificity.
• Various electrochemical signal generation methods exist, but a comprehensive summary for multiplexed interfaces is lacking.

Purpose of the Study:

• To review and classify recent advancements in electrochemical signal substances for multiplexed immunosensing interfaces.
• To provide a comprehensive overview of signal substance selection for simultaneous detection of multiple tumor markers.

Main Methods:

• Literature review focusing on the classification of labeled electrochemical signal substances.
• Analysis of state-of-the-art developments in electrochemical immunosensing interface design.

Main Results:

• Summarized various electrochemical signal substances (organic molecules, metal ions, nanoparticles, Prussian blue) used in multiplexed biosensors.
• Highlighted the importance of signal substance selection for effective simultaneous tumor marker detection.

Conclusions:

• The review provides a comprehensive summary of signal substance selection for researchers in electrochemical sensing.
• Future prospects for electrochemical signal substances in multiplexed immunosensors are discussed, aiming for improved signal generation.