Related Experiment Video
Updated: Oct 7, 2025

In Vivo Imaging of Leishmania infantum-infected Hamsters by Gingival Inoculation of Axenic Amastigotes Expressing Luciferase
Published on: April 4, 2025
Rabbit-derived human Thelazia callipaeda infection: a case report
Qingmei Tian1, Jicun Qian2, Yuhui Zhao3
1Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, No. 48#, Yingxiongshan Road, Jinan 250002, P. R. China; Shandong University of Traditional Chinese Medicine, No. 16369#, Jingshi Road, Jinan 250014, P. R. China; Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases; Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases in Universities of Shandong; Shandong Academy of Eye disease Prevention and Therapy, No. 48#, Yingxiongshan Road, Jinan 250002, P. R. China.
A medical student contracted Thelazia callipaeda eye infection after rabbit contact during an experiment. Prompt removal and treatment resolved the infection, emphasizing safety education for students.
Area of Science:
- Ophthalmology
- Parasitology
- Medical Education
Background:
- Thelazia callipaeda, a zoonotic eyeworm, can infect humans, particularly in regions with rabbit populations.
- Animal handling in educational settings presents potential risks for zoonotic disease transmission.
Observation:
- A 19-year-old medical student developed a Thelazia callipaeda infection after ocular exposure to rabbit hair during a class experiment.
- The student self-removed one worm with a cotton swab before seeking medical attention for the remaining two.
Findings:
- Ophthalmic examination confirmed the presence of three Thelazia callipaeda worms, identified as female.
- Treatment with ofloxacin and peranapulin eye drops effectively managed the inflammation.
- Follow-up examinations at two weeks and one month showed no residual abnormalities.
Implications:
- This case underscores the importance of rigorous health and safety protocols during animal-related laboratory classes for medical students.
- Enhanced education on zoonotic disease prevention, including hand hygiene after animal contact, is crucial.
- Early detection and prompt treatment are key to managing Thelazia callipaeda ocular infections.

