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Updated: Oct 7, 2025

Preventing the Spread of Malaria and Dengue Fever Using Genetically Modified Mosquitoes
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iGEM and Gene Drives: A Case Study for Governance

Piers Millett1, Tessa Alexanian1, Megan J Palmer1

  • 1Piers Millett, PhD, is Vice President for Safety and Security and Tessa Alexanian is a Safety and Security Program Officer; both at iGEM Foundation, Cambridge, MA. Megan J. Palmer, PhD, is a Bio Policy and Leadership Initiatives and Adjunct Professor, Department of Bioengineering, Stanford University, Stanford, CA. Sam Weiss Evans, DPhil, is a Senior Research Fellow, Program on Science, Technology, and Society, Harvard University, Cambridge, MA. Todd Kuiken, PhD, is a Senior Research Scholar, Genetic Engineering and Society Center, North Carolina State University, Raleigh, NC. Kenneth Oye, PhD, is a Professor of Political Science and Director of the Program on Emerging Technologies, Massachusetts Institute of Technology, Cambridge, MA.

Health Security
|January 12, 2022
PubMed
Summary

Gene drives require special governance due to their potential impact. Lessons from the International Genetically Engineered Machine (iGEM) competition highlight adaptive risk management and broader expertise integration for effective gene drive policy development.

Keywords:
Adaptive governanceAdaptive risk managementGene drivesGovernanceRisk managementiGEM

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