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Published on: October 13, 2021
Copper Metal Organic Polyhedron (Cu-MOP) Hydrogel as Responsive Cytoprotective Shell for Living Cell Encapsulation
Yu Qin1, Linlin Chen2, Yi Cheng1
1Key Laboratory of Medicinal Chemistry for Natural Resource, Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China.
Abstract:
Single-cells coated with functional shells to protect them from external harsh condition have great potential applications in many fields such as tissue engineering, cell-based devices, cell biology, and so on. Herein, copper metal organic polyhedron (Cu-MOP) hydrogel has been applied as a soft shell for cell protection under both physical and chemical stimulations. Compared with a previous strategy, this MOP-Gel shell not only possesses more satisfied protection effect but also could be prepared and removed facilely without any damage to the encapsulated cells.

