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Published on: August 7, 2017
Infant feeding practices and asthma in children aged 6 months to 5 years using a propensity score approach
Chukwuemeka E Ogbu1, Samuel Fongue2, Stella C Ogbu3
1College of Public Health, University of South Florida, Tampa, Florida, United States of America.
Insights
Exclusive breastfeeding protects children from asthma. Early formula introduction and weaning before six months increase asthma risk in young children, highlighting the importance of breastfeeding guidelines.
Area of Science:
- Pediatric Health
- Epidemiology
- Public Health
Background:
- Asthma is a prevalent chronic respiratory disease in children.
- Early life feeding practices are hypothesized to influence asthma development.
- Understanding these associations is crucial for public health interventions.
Purpose of the Study:
- To investigate the relationship between exclusive breastfeeding, early formula introduction, early weaning, and childhood asthma.
- To analyze these associations in a representative sample of US children aged 6 months to 5 years.
- To utilize a propensity score matching approach to control for confounding factors.
Main Methods:
- Data from the National Survey of Children's Health (2012-2018) was analyzed.
- Propensity score matching (PSM) was employed to create comparable groups of children with and without asthma.
- Logistic regression and chi-squared tests were used for statistical analysis.
Main Results:
- Exclusive breastfeeding demonstrated a protective effect against asthma.
- Formula feeding before 6 months was significantly associated with an increased risk of asthma.
- Early weaning before 6 months was also linked to a higher incidence of childhood asthma.
Conclusions:
- Public health systems should reinforce exclusive breastfeeding guidelines.
- Emphasizing exclusive breastfeeding in early childhood interventions can help reduce infant asthma incidence.
- These findings support WHO recommendations for breastfeeding in developed nations.
Objectives:
We examined the association between exclusive breastfeeding, early introduction of feeding formula, early weaning, and asthma in children aged six months to five years in a sample of non-institutionalized US children using a propensity score approach.
Methods:
Our study used data from the National Survey of Children's Health (2012-2018) of 3,820 children with physician-diagnosed asthma aged 6 months to 5 years. Propensity score matching (PSM) was applied to control selection bias with age, sex, race, birth weight, Federal Poverty Level, parent's education, and parent smoking history used as covariates in PSM. The total number in the matched sample was 6,904 (3,452 non-asthmatics; 3,452 asthmatics). Matched and unmatched samples were analysed using the χ2 test and multiple logistic regression.
Results:
Exclusive breastfeeding was protective against asthma in the pre-matching (AOR 0.72; 95% CI: 0.54-0.97; p = 0.03) and post-matching (AOR 0.66; 95% CI: 0.55-0.81; p < 0.001) samples. Formula feeding before 6 months was associated with asthma in unmatched (AOR 1.38; 95% CI: 1.15-1.66; p < 0.001) and matched (AOR 1.31; 95% CI: 1.16-1.47; p < 0.001) sample. Early weaning before 6 months was associated with asthma in unmatched (AOR 1.62; 95% CI: 1.35-1.54; p < 0.001) and matched sample (AOR 1.37; 95% CI: 1.23-1.54; p < 0.001).
Conclusion:
Public health systems should continue to recommend the implementation of the World Health Organization exclusive breastfeeding guideline in developed countries. Asthma interventions in children under two years should continue to emphasize exclusive breastfeeding to reduce the incidence of infant asthma.
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