Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optimality principle in vascular bifurcation.

S Oka1, M Nakai

  • 1National Cardiovascular Center Research Institute, Osaka, Japan.

Biorheology
|January 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Predictive capability of material screening by fast neutron activation analysis using laser-driven neutron sources.

The Review of scientific instruments·2022
Same author

Super-strong magnetic field-dominated ion beam dynamics in focusing plasma devices.

Scientific reports·2022
Same author

Author Correction: Proof-of-principle experiment for laser-driven cold neutron source.

Scientific reports·2021
Same author

Dosimetric calibration of GafChromic HD-V2, MD-V3, and EBT3 films for dose ranges up to 100 kGy.

The Review of scientific instruments·2021
Same author

Proof-of-principle experiment for laser-driven cold neutron source.

Scientific reports·2020
Same author

Relativistic magnetic reconnection in laser laboratory for testing an emission mechanism of hard-state black hole system.

Physical review. E·2020
Same journal

Layer-specific residual stretch changes along the human aorta: Effects of age, gender, and circumferential quadrant.

Biorheology·2025
Same journal

The effect of particle seeding on the rheological properties of blood Analog fluid used during laser Doppler velocimetry.

Biorheology·2025
Same journal

Biomechanical changes in abdominal aortic aneurysms involve a prolonged post-failure phase.

Biorheology·2025
Same journal

Examination of hemorheological and exerkine concentrations at four-week whole body vibration exercise in obese women: A pilot study.

Biorheology·2025
Same journal

Measurement of adhesive strength between the epidermal and inner tissues of plant stems using a tensile tester.

Biorheology·2025
Same journal

Blood rheology and systemic oxidative status in patients with acromegaly.

Biorheology·2025
See all related articles

The study reveals optimal vascular bifurcation geometry based on minimum energy principles. Vessel size and branching angles adapt to blood and vessel wall metabolic needs for efficient blood flow.

Area of Science:

  • Cardiovascular physiology
  • Biomechanics
  • Fluid dynamics

Background:

  • Vascular bifurcations are critical for blood flow distribution.
  • Understanding optimal geometry is key to preventing vascular diseases.
  • Energy expenditure influences vessel structure.

Purpose of the Study:

  • To determine the optimal geometry of vascular bifurcations.
  • To analyze energy costs associated with blood viscosity and cellular metabolism.
  • To relate optimal geometry to blood and vessel wall characteristics.

Main Methods:

  • Application of the principle of minimum work.
  • Modeling energy expenditure for blood viscosity.
  • Modeling energy expenditure for maintaining metabolic states of blood cells and vessel wall.

Related Experiment Videos

Main Results:

  • Optimal vessel radii and branching angles depend on morphologic and metabolic parameters.
  • In symmetrical bifurcations, increased vessel wall metabolic demand leads to smaller relative branch radii (0.794 to 0.758).
  • Increased vessel wall metabolic demand also leads to larger branching angles (37.5 to 48.7 degrees).

Conclusions:

  • Vascular bifurcation geometry is optimized to minimize overall energy expenditure.
  • Metabolic demands of blood and vessel walls are key determinants of optimal vascular structure.
  • These findings provide insights into the adaptive mechanisms of the circulatory system.