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Updated: Oct 6, 2025

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
Published on: October 6, 2016
Sarcopenia Related to Human Immunodeficiency Virus: Protective Effects of Exercise
Rafael Deminice1, Vitor H F Oliveira2, Allison R Webel2
1Department of Physical Education, Londrina State University, Londrina, Paraná, Brazil.
Abstract:
We discuss recent evidence supporting the hypothesis that sarcopenia is an emerging health concern among people with human immunodeficiency virus (HIV) because of increasing life expectancy and HIV- and treatment-related comorbidities. We also hypothesize that combined exercise at higher intensity has a key role in managing sarcopenia in this population because it directly (increases muscle strength and stimulates hypertrophy) and indirectly (prevents mitochondrial dysfunction, oxidative stress, and persistent inflammation) counteracts sarcopenia hallmarks.
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