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Published on: August 1, 2019
Obstetrical randomized controlled trials: individuals screened, approached, and enrolled
Kelly C Ditter1, Ellen H Crowe1, Hector Mendez-Figueroa1
1Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX.
This study found that obstetrical randomized clinical trials (RCTs) have a low assessed-to-enrolled ratio, indicating broad patient recruitment. Most eligible individuals are willing to participate, supporting the representativeness of study populations in obstetrics.
Area of Science:
- Obstetrics and Gynecology
- Clinical Trial Methodology
- Biostatistics
Background:
- Randomized clinical trials (RCTs) assume study groups mirror the general patient population.
- Concerns exist regarding the representativeness of obstetrics RCT populations.
- High assessed-to-enrolled ratios in past trials have raised generalizability questions.
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