Challenges and opportunities in micro/nanofluidic and lab-on-a-chip

Fluidic systems are prevalent in many areas of science due to its advantage in miniaturization, development of unique tools for diseases diagnosis and biomolecule separation. In the chapter, we will describe some of the key features of microfluidic/nanofluidic (MF/NF) and lab-on-a-chip system in diverse field over the past years. In addition, we will highlight the major challenges for the microfluidic/nanofluidic and lab-on-a-chip system. All-purpose and universal micro/nanofluidic platforms that can perform multiplexed assays on real biological samples are in high demand. However, the adoption of novel microfluidic devices has been carried out at a slow pace due to translation gap in development of new devices to realization into commercialization. By addressing the challenges of system integration, low-cost technology availability, rapid regulatory approval, and clinical acceptance, a pipeline of promising microdevice technologies can be developed.