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Published on: August 7, 2019
[Rapid diagnosis for liquid-based fine needle aspiration of thyroid nodules]
Alexia Gazeu1, Christine Cugnet Anceau2, Lucie Ravella1
1Service d'anatomie et cytologie pathologiques, hôpital Lyon Sud, hospices civils de Lyon, Pierre-Bénite, France.
Introduction:
The discovery of thyroid nodule can be a source of concern for the patient. Fine-needle aspiration is the gold standard for their evaluation. We establish a new rapid diagnosis procedure for liquid-based fine needle aspiration (LB-FNA) of thyroid nodules.
Methods:
Patients were admitted in a day hospital program and a FNA was performed under ultrasound monitoring guidance. The sample followed a dedicated emergency circuit, and the technique was performed within 2 hours.
Results:
A total of 92 fine needle aspirations were performed between June 2018 and March 2020. Our results showed 21% cases of nondiagnostic, 50% of benign, 21% of atypia of undetermined significance, 2% of follicular neoplasm, 1% of suspicious for malignancy and 5% of malignant. Thanks to these results, 18 patients underwent surgery: 3 benign and 3 nondiagnostic (corresponding to 100% of benign follicular nodules), 2 follicular neoplasm (100% Hürthle cell adenomas), 1 suspicious for malignancy and 3 malignant (100% papillary carcinoma), 6 atypia of undetermined significance (83% of benign lesions, 17% non invasive follicular nodules).
Conclusion:
Rapid diagnosis for thyroid nodules LB-FNA is possible, requiring a specific network involving radiologists, endocrinologists, cytopathologists and surgeons. This is an easy and effective method to improve the quality of patient care.
